Hypoparathyroidism causes low levels of calcium in your blood. Learn the symptoms and about treatment. Hypoparathyroidism is a deficiency of parathyroid hormone often caused by an autoimmune disorder or by iatrogenic damage or removal of the parathyroid glands during thyroidectomy or parathyroidectomy. Symptoms of hypoparathyroidism are due to hypocalcemia and include tingling in the hands or around the mouth and muscle cramps. Onset of the disease is very gradual and symptoms can be mild. Many people diagnosed with hypoparathyroidism have had symptoms for years before they are diagnosed. Symptoms may be so mild that the diagnosis is made after a screening blood test that shows low calcium. Symptoms may include any of the following: Tingling lips, fingers, and toes (most common) Muscle cramps (most common) Muscle. 5 Common Symptoms of Hypoparathyroidism Read about the symptoms of hypoparathyroidism, a condition that occurs when your parathyroid glands fail to produce enough parathyroid hormone (PTH). Hypoparathyroidism is a rare disorder in which the body produces too little or no parathyroid hormone. This hormone, together with vitamin D and another hormone called calcitonin, regulates the amount of calcium in the blood. Hypoparathyroidism can result in an abnormally low level of calcium in the blood, called hypocalcemia. Understand hypoparathyroidism, including the causes and symptoms of an under-functioning parathyroid, as well as diagnosis and treatments. Hypoparathyroidism is a rare condition in which the body doesn't make enough of a key hormone called parathyroid hormone (PTH). PTH helps control and maintain the right balance of two minerals in the body: calcium and phosphorus. With hypoparathyroidism, too little PTH leads to unusually low levels of calcium in the blood. It also leads to high levels of phosphorous in the blood. What are the symptoms of hypoparathyroidism? The main symptoms 1 of hypoparathyroidism are: tingling pins and needle sensations muscle cramps/spasms How is it diagnosed? Hypoparathyroidism is diagnosed by looking at calcium and parathyroid hormone levels in the blood and urine. How is hypoparathyroidism treated? Hypocalcemia due to hypoparathyroidism causes a wide range of symptoms, from numbness in the fingers and toes to severe muscle pain. Learn more about the five main symptoms you may experience if you have hypoparathyroidism, and what may cause them to occur.